![]() Modifying meiotic recombination has the potential to accelerate plant breeding but it can also have detrimental effects on plant performance by breaking beneficial genetic linkages. Accordingly, meiotic recombination drives genome evolution and is a powerful tool for breeders to create new varieties important to food security. ![]() Meiotic recombination also influences centromere organization and is essential for proper chromosome segregation. Repair of meiotic DSBs facilitates the pairing of homologs and forms crossovers which are the reciprocal exchange of genetic information between chromosomes. During meiosis, a large number of programmed DNA double-strand breaks (DSBs) are formed throughout the genome. Meiosis is a specialized cell division that contributes to halve the genome content and reshuffle allelic combinations between generations in sexually reproducing eukaryotes. 2Institut Génétique Reproduction et Développement (iGReD), Université Clermont Auvergne, UMR 6293 CNRS, U1103 INSERM, Clermont-Ferrand, France. ![]()
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